|
|
|
|
EDITED BY PROFESSOR YASSER METWALLY |
|
|
|
The use of antiplatelet agents for secondary
prevention of stroke |
|
Stroke is a leading cause of death and the primary cause of serious,
long-term disability in the United States. Joint guidelines from the
American Heart Association (AHA) and American Stroke Association
(ASA), as well as recent guidelines from the Eighth American College
of Chest Physicians (ACCP) Conference on Antithrombotic and
Antiplatelet Therapy, recommend aspirin, clopidogrel, or
extended-release dipyridamole plus aspirin as acceptable firstline
options for secondary prevention of ischemic events in patients with
a history of ischemic stroke or transient ischemic attack (TIA). |
>>> Click
to download the neurology bulletin>>>
|
The safety of Antiplatelet agents for stroke prevention |
|
Aggressive secondary prevention is critical to improving long-term
outcomes in patients with ischemic coronary artery disease,
cerebrovascular disease, and peripheral artery disease. An essential
component of successful secondary prevention is antiplatelet therapy,
which in most patient populations consists of aspirin, clopidogrel,
aspirin plus clopidogrel, or aspirin plus extended-release
dipyridamole. As is true for any pharmacologic agent, benefits must
be balanced with risks. For antiplatelet agents, the most important
risk is excess bleeding, especially as emerging evidence suggests
that excess bleeding is associated with adverse long-term outcomes;
thus prevention and management of excess bleeding is critically
important. In addition, recommendations for avoidance and management
of minor adverse events are described so that patients maintain drug
adherence. Overall, aspirin, clopidogrel, aspirin plus clopidogrel,
and aspirin plus extended-release dipyridamole have favorable
risk-versus-benefit profiles when used as recommended in appropriate
patient populations. |
>>> Click
to download the neurology bulletin>>>
|
The role of antiplatelet agents in the
management of transient ischemic attacks |
|
As many as 300,000 transient ischemic attacks (TIAs) occur in the
United States each year, accounting for 0.3% of all Emergency
Department visits. An under-recognized and under-treated problem, TIA
is associated with up to a 10% risk of subsequent stroke within 7
days and a 25% risk of death at 1 year. Antiplatelet therapy can
result in significant reductions in secondary stroke risk. However,
nearly 50% of patients with TIA leave the Emergency Department
without any medication. This article discusses recent results from
major antiplatelet clinical trials in stroke prevention and
highlights the need for appropriate and timely initiation of
antiplatelet treatment in patients with TIA. |
>>> Click
to download the neurology bulletin>>>
|
Stroke in children: A study of 4 cases |
>>> Click
to download the neurology bulletin>>>
|
Hemorrhagic transformation is common in patients with supratentorial
and cerebellar embolic stroke.[1] Embolus migration with a subsequent
reestablishment of the blood flow into the infarcted tissue
(migratory embolism) probably accounts for most hemorrhagic
transformations. Pathological examinations of pontine infarction
often show petechial hemorrhages, but massive hemorrhagic infarction
is relatively uncommon. |
>>> Click
to download the neurology bulletin>>>
|
Downloadable multiple choice questions software |
|
A downloadable software featuring 5 full radiological cases with
applied self- checking multiple choice questions on every case, you
can email the result to the author for evaluation and discussion. The
software is a freeware, a gift not to sold. You are free to use the
software for any educational purposes you want and to distribute it
on a non-profit basis. A new version of the software is available
every month and remains available for one month (The available
version now is version 3.4, February 2010), the software version is
changed with the monthly update of the bulletin. |
>>>Click
here to download the current version of the multiple choice
questions software>>> ....(Click
here to get a better idea about this publication)
|
Downloadable single case study software |
|
A downloadable software featuring a full radiological study of a
single case with a radiological report and a review of literature.
You can email the author from within the software. The software is a
freeware, a gift not to sold. You are free to use the software for
any educational purposes you want and to distribute it on a
non-profit basis. A new version of the software is available every
month and remains available for one month (The available version now
is version 4.3, February 2010), the software version is changed with
the monthly update of the bulletin. |
>>>Click
here to download the current version of the single case study software>>> ....(Click
here to get a better idea about this publication)
|
A downloadable, weekly updated, neurological case with full clinical,
radiological and pathological data. You can email the author from
within the downloaded software. The software is a freeware, a gift
not to sold. You are free to use the software for any educational
purposes you want and to distribute it on a non-profit basis. A new
version of the software is available every week and remains available
for one week, it is updated every Saturday. |
>>>Click
here to download the case of the week software>>>
....(Click
here to get a better idea about this publication)..
The
PDF version | The
Short case version | Archive
of long cases | Archive
of short case | Case
records
|
A monthly updated PDF file fully addressing a single topic in the
field of neurology, psychiatry or neurosurgery. The PDF file is
changed with the monthly update of the bulletin. |
>>>Click
here to download the current issue of "topic of the month">>>.....(Click
for an archive of back issues of "topic of the month) ..(Topic
of the month)
>>>
Click
to view the radiological quiz>>> | >>>Click
to download the answer to the quiz>>>
Topic
of the month | Thesis
section | Research
section | Talking
psychiatry | Differential
diagnosis | Case
of the week
Visit my web site at: http://yassermetwally.com
Screen resolution is better set at 1024*768
pixel screen area
Copyright ©
Yasser Metwally, all rights reserved |
